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Tag:orthobiologics and pharmacologics
Wednesday, 19 August 2009
Written by David J. Hak, MD, MBA
Three important terms are used when describing bone grafts and bone graft substitutes. An understanding of these three terms (osteogenesis, osteoconduction, and osteoinduction) is an esse ...
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Monday, 17 August 2009
Written by David J. Hak, MD, MBA
In the United States, bone graft substitutes may be regulated and approved in different manners depending on specific characteristics of the product. Varying levels of safety and efficacy ...
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Monday, 20 July 2009
Written by SYSTEM
Blood management in orthopedic surgery today consists of allogenic transfusions, autologous blood, intra- and postoperative blood salvage, and erythropoietin alpha.1 In my experience, in ...
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Monday, 17 August 2009
Written by David J. Hak, MD, MBA
Bone repair following fracture has been divided into three main phases: the inflammatory phase, the reparative phase, and the remodeling phase. During the inflammatory phase prostaglandin ...
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Wednesday, 20 April 2005
Written by Thomas A. Einhorn, MD
Evidence-Based Approach to the Evaluation of Tissue Engineering in Orthopedic Surgery
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Monday, 17 August 2009
Written by David J. Hak, MD, MBA
The commercial availability of recombinant human bone morphogenetic proteins (rhBMP) has introduced a new health care expense. The relatively high cost of this product has raised economic concerns ...
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Tuesday, 31 May 2005
Written by Jonathan N. Grauer, MD
Platelet Gels
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Tuesday, 21 July 2009
Written by SYSTEM
The mainstay of postoperative analgesia for moderate or severe orthopedic procedures is oral or intravenous opioids. However, although opioids provide potent analgesia, they also cause side effects ...
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Tuesday, 31 May 2005
Written by David J. Hak, MD, M.B.A.
Osteoconductive Bone Graft Substitutes in Orthopedic Trauma
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Monday, 06 June 2005
Written by Jonathan N. Grauer, MD
Marrow Cells
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The patient is a white man aged 58 years who is newly referred to a rheumatology practice for ongoing management of his osteoarthritis...

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